WebIn both cohorts, the major determinants for recurrence and overall survival were achieving debulking at the microscopic level and complete response, regardless of the therapeutic sequence (primary debulking surgery [PDS] followed by … A total of 273 patients were included, of whom 20 (7.3%) were lost to follow-up; overall, 253 patients (92.7%) remained for the complete follow-up. The median follow-up time was 51.2 months, and the median age was 51 years (IQR: 46–60). Most patients had FIGO stage IIIC disease (n= 209, 82.6%), and 44 … See more Of the 253 patients, 90 (35.6%) were treated with PDS followed by postoperative chemotherapy, and 163 (64.4%) were treated with NACT followed by IDS … See more Of the 253 patients who completed follow-up, 46 cases (18.3%) were stable without recurrence, 207 cases (81.8%) relapsed, and 137 cases (54.2%) died. … See more For all 163 patients in the IDS group, the median number of NACT cycles was 3 (IQR: 3–4); the median number of postoperative chemotherapy cycles was 6 (IQR: … See more
COUNTERPOINT: Primary Debulking Surgery vs Neoadjuvant …
WebProgression-free survival (PFS) was assessed by surgical status (primary debulking surgery [PDS] vs neoadjuvant chemotherapy/interval debulking surgery [NACT/IDS]) and postoperative residual disease status (no visible residual disease [NVRD] vs visible residual disease [VRD]) in the intent-to-treat population. WebJun 1, 2024 · 5509 Background: Most pts with EOC relapse after PDS and ct. Autologous DCVAC can present tumor antigens to elicit a durable immune response. We hypothesized … queen elizabeth kids hospital
Primary debulking surgery vs. interval debulking surgery for …
WebNov 30, 2024 · Historically the standard treatment approach for advanced ovarian cancer has been to perform up-front primary cytoreduction surgery or primary “debulking” surgery (PDS) followed by adjuvant chemotherapy. The goal of surgery was to establish cytoreduction of the tumor to optimal (<1 cm 3 disease) or, ideally, complete (no gross … Webprimary debulking surgery（PDS） 39, 50, 59, 63, 92, 95, 96, 156 PVB療法 42, 177, 185 R risk-reducing salpingo-oophorec-tomy（RRSO） 51, 68 S S─1 89 salvage chemotherapy 40 SCC 164, 165 SCOTROC1 82 secondary debulking surgery （SDS） 39, 130, 139, 165, 174 second─line chemotherapy 40 SEER 52, 119, 124, 163, 182, 183 WebFeb 21, 2024 · It is debated whether women with FIGO (International Federation of Gynecology and Obstetrics) Stage IV epithelial ovarian cancer should be offered primary … queen elizabeth key life events