Web10 apr. 2024 · Subchondral bone sclerosis is a major feature of osteoarthritis (OA), and bone marrow mesenchymal stem cells (BMSCs) are presumed to play an important role in subchondral bone sclerosis. Accumulating evidence has shown that stromal cell-derived factor-1α (SDF-1α) plays a key role in bone metabolism-related diseases, but its role in … Web6 apr. 2024 · A mechanical niche promotes the rejuvenation of blood stem cells. Zhang et al. show that the mechanical properties of a three-dimensional (3D) hydrogel can …
Bone Marrow: Anatomy, Function, and Treatment - Verywell Health
WebIn addition to the source of the stem cell, other aspects are critical for successful tissue engineering, such as the biomaterial to be selected as a scaffold and the correct linkage between them. 22 To regenerate the bone tissue defect, the selected biomaterial must allow cells to migrate, proliferate, and differentiate into bone cells, but local angiogenesis is … WebHuman mesenchymal stem cells (MSCs) have increasingly been used as cellular vectors for the delivery of therapeutic genes to tumors. ... Matrix metalloproteinase 1 is … オリゴのおかげ
Exosomes derived from EphB2-overexpressing bone marrow mesenchymal stem ...
WebAlthough hypoxic environments have been known to regulate the migratory ability of bone marrow-derived mesenchymal stem cells (BM-MSCs), which is a critical factor for maximizing the therapeutic effect, the underlying mechanisms remain unclear. Therefore, we aimed to confirm the effect of hypoxia-inducible factor-1 α (HIF-1 α >) on the migration … Web3 mei 2024 · A three-dimensional migration assay was performed to investigate the collective migration of BM-MSCs, maintaining cell-cell adhesion, toward breast tumor … Web1 jun. 1999 · All mature blood cells are derived from the haemopoietic stem cell (HSC). In common with all other haemopoietic cells, stem cells are mobile, and it is this property of mobility that has allowed bone marrow transplantation to become a routine clinical option. Successful transplantation requires haemopoietic stem cells to home to the bone … オリゴヌクレオチド 構造