2024 Lamp1 自噬溶酶体

Lamp1 自噬溶酶体

Author: azlm

August undefined, 2024

TīmeklisLysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular localization of lysosomal membrane proteins in five mammalian cultured cell lines. Rat LAMP1 fused to enhanced green fluorescent protein (EGFP) mostly accumulate … TīmeklisLysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular localization of lysosomal …

溶酶体相关膜蛋白LAMP1与肿瘤相关性的研究进展 - 百度学术

TīmeklisLAMP1 was immunoprecipitated from 0.35 mg of NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate with ab208943 at 1/30 dilution. Western blot was performed from the immunoprecipitate using ab208943 at 1/1000 dilution. VeriBlot for IP Detection Reagent (HRP) , was used for detection at 1/10000 dilution. Tīmeklis2024. gada 10. sept. · 细胞器标志物丨LAMP1抗体. 溶酶体相关膜蛋白1（LAMP1）也称为CD107a（分化簇107a）。. LAMP1/CD107a属于灯系列。. 这种糖蛋白为选择素 … pink velvet ottoman stool

Characterization of LAMP1-labeled nondegradative lysosomal and …

Tīmeklis2024. gada 30. marts · Present results indicate that prolonged treatment with SUN affects LAMP1 and LAMP2 expression only marginally in most patients. In contrast, changes in ATP6V1B2 expression were marked and resembled irregular oscillations. Very similar changes in the expression of lysosomal membrane proteins were also … Tīmeklis2024. gada 10. sept. · 溶酶体相关膜蛋白1（LAMP1）也称为CD107a（分化簇107a）。. LAMP1/CD107a属于灯系列。. 这种糖蛋白为选择素提供碳水化合物配体。. 它也可 … TīmeklisLAMP1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 LAMP 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。 LAMP1 和 LAMP2 的蛋白序列有 37% 同源性。 LAMP1 和 LAMP2 均在溶酶体-吞噬体融合与胆固醇运输期间参与调节溶酶体的运动性 (5,6)。 Eskelinen, E.L. et al. (2003) Trends Cell Biol 13, 137-45. Fukuda, M. (1991) J Biol … pink velvet vanity stool

细胞器常用蛋白marker全攻略（上） - 知乎 - 知乎专栏

Tīmeklis自噬（autophagy=self-eating）意为自体吞噬，是真核细胞在自噬相关基因（autophagy related gene，Atg）的调控下利用溶酶体降解自身细胞质蛋白和受损细胞器的过程。 … Tīmeklis参与成熟阶段的溶酶体相关蛋白还包括： lamp1、 lamp2、 uvrag(紫外线抵抗相关肿瘤抑制基因)。 5）自噬体的裂解阶段：是指自噬溶酶体膜的裂解及内容物在溶酶体水解 … pink vermillionTīmeklis2024. gada 3. sept. · Our study demonstrates that a significant portion of LAMP1-labeled organelles do not contain detectable lysosomal hydrolases including cathepsins D … pink venom violin sheet music

"Tīmeklis2008. gada 23. sept. · LAMP1 DMDM 206729915 ClinGen HGNC:6499 GenCC HGNC:6499 PTM/Processing Features Showing features for signal, chain, glycosylation, disulfide bond. Expand table Post-translational modification O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. The glycosylation of N … " - Lamp1 自噬溶酶体

Lamp1 自噬溶酶体

LAMP1 expression is associated with poor prognosis in breast …

TīmeklisThe lysosomal membrane proteins LAMP-1 and LAMP-2 are estimated to contribute to about 50% of all proteins of the lysosome membrane. Surprisingly, mice deficient in … TīmeklisMilana Fraiberg, Zvulun Elazar, in Progress in Molecular Biology and Translational Science, 2024. 3.4 LAMP2. The LAMP2 gene is located on the Xq24 chromosome. Lysosome-associated membrane protein-2 (LAMP2), together with LAMP1, comprises a major protein component of lysosomal membranes.LAMP2 is a type I …

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Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. … Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and … Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an … Skatīt vairāk

TīmeklisWild-type (WT) and LAMP1 knockout (KO) HeLa cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with LAMP1 antibody [GT25212] (GTX634336) diluted at 1:10000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Tīmeklislamp1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 lamp 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。lamp1 和 lamp2 的蛋白序列有 37% 同源性。lamp1 和 lamp2 均 …

Tīmeklis2024. gada 6. janv. · LAMP1 has a molecular mass of between 90 and 120 kDa, and is heavily glycosylated with a large number of N-glycans and some O-glycans (Fukuda 1991; Eskelinen et al. 2003 ). The N-glycans of LAMP1 and LAMP2 protect against proteolytic degradation in lysosomes (Kundra and Kornfeld 1999 ). Tīmeklis2024. gada 28. jūl. · LAMP1/2 是溶酶体相关膜蛋白，相关抗体可用于标记溶酶体。自噬信号通路的研究自噬在细胞存活与死亡中是把双刃剑，既能促进细胞存活也会导致 …

Tīmeklis2005. gada 15. nov. · High levels of LAMP1-GFP overexpression elicited aberrant aggregation of late endocytic organelles, a phenomenon that probably involved formation of anti-parallel dimers of LAMP1-GFP as it was not observed in cells expressing comparable levels of a non-dimerizing mutant variant, LAMP1-mGFP. To …

Tīmeklis自噬是一种溶酶体介导的降解系统，是一种进化上保守的途径，用于循环利用细胞内容物，清除聚集的蛋白质、受损的细胞器和入侵的病原体 (如病毒和细菌)，以维持正常的 … hai dokumentation kinderTīmeklis再次探讨LAMP1作为神经系统中降解自噬-溶酶体细胞器的标志物溶酶体充当宏自噬/自噬和胞吞成分的降解中心，因此维持了神经元存活和功能必不可少的细胞稳态。 … pink vanna slippersTīmeklislamp1质量控制：＞95%(还原性sds-page) lamp1制剂：冻干品 lamp1保存：冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。复溶蛋白溶液可在4～7℃保 … pink ventolin inhalerTīmeklis2024. gada 15. dec. · 自噬体与溶酶体的直接融合形成自噬溶酶体，形成过程中主要是 LAMP1、Rab7、UVRAG 和 Rubicon 的参与。降解及再循环利用 ATG9 作为唯一 … pink vaseline lip therapyTīmeklis2024. gada 27. jūl. · LAMP1，即溶酶体相关膜蛋白1，又称CD107a、是单层膜结构的囊泡状细胞器，内含多种酸性水解LAMP-A、lgp120，最早于1985年由Chen等 [10]和 … pink vernissage tomatoTīmeklisLAMP1 - lysosomal associated membrane protein 1 Gene 基因蛋白疾病直系同源中文名称：溶酶体相关膜蛋白 1 种属: Homo sapiens 同用名: LAMPA; CD107a; LGP120 基因 ID: 3916 基因类型: protein coding 关于 LAMP1 Cytogenetic location: 13q34 Genomic coordinates (GRCh38): 13:113,297,239-113,323,672 (from NCBI) This gene has 3 … hai dokumentationenTīmeklisLAMP-1 Antibody (H4A3) is an IgG 1 κ mouse monoclonal LAMP-1 antibody (also designated LAMP1 antibody or CD107a antibody) that detects the LAMP-1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. LAMP-1 Antibody (H4A3) is available as both the non-conjugated anti-LAMP-1 antibody form, as well as … pink velvet ottoman closet