WebMar 20, 2024 · In the study of FoxM1 in gastric cancer, FoxM1 could inhibit cell apoptosis and promote proliferation of gastric cells . FoxM1 also played a vital role in promoting angiogenesis and lymph node metastasis by regulating the expression of MMP in gastric cancer . Besides, the researchers found FoxM1 could participate in regulating the … WebSep 20, 2016 · In the present study, FoxM1 silencing was found to enhance docetaxel-induced A549/DTX cell apoptosis through augmenting the increase of Bax/Bcl-2 ratio, the Bax mitochondrial translocation, the activation of caspase-3 and caspase-9, as well as the decrease of cytochrome c in mitochondria.
CDI Exerts Anti-Tumor Effects by Blocking the FoxM1-DNA …
WebOct 2, 2012 · In gastric cancer, Zeng et al. showed that FoxM1 was overexpressed in gastric cancer and its inhibition led to cellular senescence, which depended on p27 kip1. 28 Furthermore, Li et al. 29 … WebMar 1, 2024 · The inhibition of uncontrolled cell proliferation is crucial to hindering ... Total saponins from Tupistra chinensis baker inhibits growth of human gastric cancer cells in vitro and in vivo. J Ethnopharmacol 278, 114323. 10.1016 ... FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self ... pottery class west seattle
JCI - Coordinated activation of c-Src and FOXM1 drives tumor cell ...
WebSep 3, 2013 · FOXM1 amplification was identified as an independent prognostic factor in gastric cancer (P = 0.001), and its affection is more significant in patients with tumor size larger than 5 cm (P = 0.004), pT3-4 (P = 0.003) or pIII-IV (P = 0.001). WebOct 24, 2013 · In the present study, we show that Twist 1 overexpression leads to a significant up-regulation of FoxM1, which plays a key role in cell cycle progression in … WebJan 29, 2009 · When FoxM1 in gastric cancer cells was knocked-down, impaired clonogenicity and cellular senescence occurred independently of p53 and p16 status. … tour hack