Condition gwas
WebApr 10, 2024 · The projected rise in global ambient temperature by 3–5 °C by the end of this century, along with unpredicted heat waves during critical crop growth stages, can drastically reduce grain yield and will pose a great food security challenge. It is therefore important to identify wheat genetic resources able to withstand high temperatures, … WebJun 18, 2024 · Body surface area (BSA) is an important trait used for many clinical purposes. People’s BSA may vary due to genetic background, race, and different lifestyle factors (such as walking, exercise, reading, smoking, transportation, etc.). GWAS of BSA was conducted on 5,324 subjects of four ethnic populations of European-American, …
Condition gwas
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WebNov 2, 2024 · GWAS analysis of the 193 accessions used in the current study was performed to discover the natural genetic variation of the studied traits. We detected a total of 338 significant marker-trait associations with –log 10 p-value ≥3 of which 111 SNPs passing FDR test ( S2 Table ) distributed over the barley chromosome seven. WebFeb 13, 2024 · However, the significance of the SNPs in the first region on chromosome 15 (58.5 Mb–60.5 Mb) in the conditional analysis differed from the original GWAS depending on the LD between the SNPs and MARC0083357; e.g., the P-value for H3GA0044376 in the conditional GWAS was only 0.017 whereas the original P-value was 4.910E-07 (r 2 with …
WebApr 13, 2024 · HIGHLIGHTS. who: Nguni Cattle Coat Colour et al. from the Discipline of, School of Life Sciences, University of KwaZulu-Natal, Scottsville, South Africa, Agricultural Research have published the article: Genetics of Base Coat Colour Variations and Coat Colour-Patterns of the South African Nguni Cattle Investigated Using High-Density SNP … WebWe here review the conditional false discovery rate (condFDR) method, a model-free strategy for analysis of GWAS summary data, which has improved yield of existing GWAS and provided novel findings of genetic overlap between a wide range of complex human phenotypes, including psychiatric, cardiovascular, and neurological disorders, as well as ...
WebJun 15, 2024 · Seedling vigor is a desirable trait in direct-seeded rice (Oryza sativa L.) to improve plant establishment and enhance weed competition.In this study, a genome-wide association study (GWAS) on seedling vigor traits was performed on a rice panel of 244 accessions consisting of the five major rice subpopulations (aromatic, aus, tropical … WebAug 26, 2024 · Genome-wide association studies (GWAS) test hundreds of thousands of genetic variants across many genomes to find those statistically associated with a specific trait or disease. This methodology ...
Web本期我们对GWAS分析做一些简单介绍。GWAS，全称genome-wide association study，即全基因组关联分析。GWAS是一种用于识别遗传区域（基因座）和性状（包括疾病）之 …
WebMar 18, 2012 · We present an approximate conditional and joint association analysis that can use summary-level statistics from a meta-analysis of genome-wide association … seattle light rail passWebApr 12, 2024 · GWAS summary data of a total of 17 independent studies related to allergic diseases were collected from the IEU GWAS database for the outcome dataset. Significant causal relationships were obtained between gut microbiome features including Ruminococcaceae , Eggerthella , Bifidobacterium , Faecalibacterium , and Bacteroides … seattle light rail redmondWebSubstantial genetic liability is shared across psychiatric disorders but less is known about risk variants that are specific to a given disorder. We used multi-trait conditional and joint analysis (mtCOJO) to adjust GWAS summary statistics of one disorder for the effects of genetically correlated traits to identify putative disorder-specific SNP associations. seattle light rail north linkWebJul 8, 2024 · A stepwise conditional multi-trait GWAS (CM-GWAS) identified putative causal variants and related genes from 178 independent quantitative trait loci (QTL) of … puget sound pilots dispatchWebJul 13, 2024 · Results. We identified 14 independent loci associated (P < 5 × 10 −8) with estradiol levels in males, of which 1 (CYP3A7) was genome-wide and 7 nominally (P < 0.05) significant in females.In addition, 1 female-specific locus was identified. Most loci contain functionally relevant genes that have not been discussed in relation to estradiol levels in … seattle light rail networkWeb20 languages. In genomics, a genome-wide association study ( GWA study, or GWAS ), is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a … puget sound perio eastlakeWebJan 28, 2024 · We propose an approximate conditional phenotype analysis based on GWAS summary statistics, the covariance between outcome and confounder, and the variant minor allele frequency (MAF). seattle light rail ridership