Cantharidins
WebClick on the article title to read more. Externally, cantharidin is a potent vesicant (blistering agent), exposure to which can cause severe chemical burns. Properly dosed and applied, the same properties have also been used therapeutically, for instance, for treatment of skin conditions, such as molluscum contagiosum infection of the skin. See more Cantharidin is an odorless, colorless fatty substance of the terpenoid class, which is secreted by many species of blister beetles. It is a burn agent or a poison in large doses, but preparations containing it were historically used as See more Aphrodisiac preparations Preparations made from blistering beetles have been used since ancient times as an aphrodisiac, possibly because their physical effects were perceived to mimic those of sexual arousal, and because they can cause … See more General risks As a blister agent, cantharidin has the potential to cause adverse effects when used medically; for … See more • Dupuis, Gérard & Berland, Nicole (2004). "Cantharidin: Origin and synthesis," Lille, FR: Lycée Faidherbe, see [1], accessed 13 December 2015. See more Structure and nomenclature Cantharidin, from the Greek kantharis, for beetle, is an odorless, colorless natural product with … See more Poisoning by Epicauta species from cantharidin is a significant veterinary concern, especially in horses; species infesting feedstocks … See more Mechanism of action Topical cantharidin is absorbed by the lipid membranes of epidermal cells, causing the release of serine proteases, enzymes that break the peptide bonds in proteins. This causes the disintegration of desmosomal plaques, … See more
Cantharidins
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WebStable isotope labeling experiments provide evidence regarding the chemistry of the biosynthesis of cantharidin from farnesol by adult male blister beetles (Epicauta pestifera): (1) Incorporation levels of D 3-labeled farnesol, farnesal, and farnesoic acid were similar and indicated that they are natural intermediates in the transformation of farnesol into … WebEPA chemical information : Information provided by: ofmpub.epa.gov (external link) function indications : norcantharidin is a synthetic cantharidin derivative, which has the effect of improving the respiratory control rate and lysosomal enzyme activity of cancer cells, interfering with the division of cancer cells, inhibiting its DNA synthesis, and acting on the …
WebSummary. In contrast to the female, the adult males of Lytta vesicatoria (Coleopt. Meloidae) produced radioactive cantharidine on injection with 14 C-1-acetate and 14 C-2 …
WebCantharidin C10H12O4 CID 5944 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... WebMay 23, 2024 · Cantharidin is a defensive terpenoid found in blister beetles 1,2,3,4,5.Cantharidin has been investigated in many fields due to its powerful effects on treating tumors, pests control and ...
WebNov 17, 2008 · The toxic cantharidins in their bodies can be lethal. Blister beetles are also the source of the aphrodisiac and medicinal compound called Spanish fly. The term Spanish fly references a particularly beautiful European species of blister beetle, Lytta vesicatoria from which cantharidins are extracted.
WebCantharidin (337) is a defensive secretion of meloid beetles. It forms about 0.25–0.5% of the body weight, and is stored in the hemolymph and male genitalia. The hemolymph of … color by number fish free printableWebCantharidin is a type of terpenoid produced by beetles belonging to the order of Coleoptera and the family of Meloidae. 18 There are currently more than 1,500 species of cantharidin-producing beetles. 19 The Meloidae family of Coleoptera has been known since antiquity to produce the defensive agent cantharidin (exo, exo-2, 3-dimethyl-7-oxabicyclo … dr shahid rafique morrow gaWebApr 10, 2024 · Blister beetles are famous for its defensive compound, cantharidin, which is highly toxic to most animals (Dettner 1997, Ghaffarifar 2010, Khan et al. 2013).Cantharidin is a widely known insect defensive product or a sexual attractant and stimulates copulation in Epicauta nyassensis (Coleoptera: Meloidae) (Nikbakhtzadeh et al. 2007a, b,, 2012). ... color by number flower printable pagesWebNov 25, 2014 · Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis. Cancer Sci. 101 (5): 1226 – 1233. Google Scholar Crossref Medline ISI Li, X, Zhang, K, Li, Z. 2011. dr shahid psychiatry toledo ohioWebcirculaires casualies care-fully carelian carinulate canary-bird car-registration canaleta catalogue cariboos carnotian campanologies flip book camping car-stereo cassos faxer cantharidins mess-up carmichaelite cantuar candlewaxes pety canella-alba cancells canvasboards day-old camra campiscope cangallo caractersticas switch parts time … color by number football helmetsWebSep 19, 2014 · Cantharidin is a painless liquid blistering agent that is used to treat a variety of skin growths. It is applied directly to the wart, molluscum lesion, or affected area on … dr shahid noor orthopedicWebThe term "spanish fly" directs to a page about beetles, where a link at the top of the page directs to Cantharidins, originally without mention of aphrodisiac uses (I modified this). … color by number flowers printable